Clearer Skin Shown in Pivotal Studies

VTAMA cream showed significant results vs vehicle at week 4 with continued improvement up to week 12 in 2 identical studies.2,6-8

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VTAMA cream showed significant results in pivotal studies

PGA treatment success: PGA score of 0 or 1 and ≥2-grade improvement from baseline to week 12 (ITT, MI)2,5-7

36% and 40% of adult patients achieved treatment success in the VTAMA cream arms vs 6% and 6% in the vehicle arms in PSOARING 1 and 2.2

Gradient

PASI75 from baseline to week 12 (ITT, MI)5,8

VTAMA cream delivered significant PASI75 rates as early as week 4 and at week 12, up to 48% of adult patients achieved PASI75 vs ~10% of those using vehicle.

ITT, intention-to-treat; MI, multiple imputation; PASI75, ≥75% improvement in Psoriasis Area and Severity Index; PGA, Physician Global Assessment.

Favorable Safety Profile2

Adverse Reactions Occurring in ≥1% of the Patients in the 12-week PSOARING 1 and PSOARING 2 Clinical Trials.

Table showing favorable safety profile results from PSOARING 1 and PSOARING 2 studies